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Table 2 Results of ATMP transport validation in dry ice

From: Logistics of an advanced therapy medicinal product during COVID-19 pandemic in Italy: successful delivery of mesenchymal stromal cells in dry ice

Delivery date Temperature (external) Delivery time Temperature (start) Temperature (arrival) Dry ice weight loss
07.04.2020 15 °C 2 h 25 min − 86.1 °C − 79.1 °C 2%
14.04.2020 20 °C 1 h 35 min − 80.3 °C − 78.9 °C 1%
05.05.2020 35 °C 24 h − 80.6 °C − 80.3 °C 30%
  1. Two concurrent and one prospective runs were performed. The temperature of the ATMP always remained below − 76 °C. The maximum delivery time was 24 h